Coverletter

Peptide Chemist, More than 10 years experience. PhD from Bielefeld University. More than 3 years at Lonza as Peptide Chemist.

• Naturwissenschaft
• Pharmazie

Dear Madam/Sir,

I got access to the website of your company which aroused my interest to apply to. I obtained Ph.D. degree in Bielefeld University in Germany in 2008. After graduation I secured a job offer from Lonza AG in Visp and worked there for more than 3 years as peptide R&D/Production chemist. I returned to China on Dec. 2011 with an aspiration for a much broader stage. I functioned as the associate director of peptide department in GenScript Inc. ever since. However, I will have to admit that I would prefer a more professional working environment. This makes me make up my mind to head for a place which is in line with my aspiration. It is the very reason for which I would like to apply for a potential position in your company. Please refer to the attached Resume of mine and check my qualification. Many thanks!

Regards

Dec. 2011 till now Associate Director, Peptide Department, GenScript Inc., Nanjing, China

Activities: Management of the peptide department (ca. 120 employees); Management of construction of cGMP production factory; General Project/Team management (Process Development); Crucial Project Evaluation/Costing; SOPs Establishment and Review; Production Organisation; Customer Communication; Market Development; Training, Innovative Technology Introduction; Outsourcing Management.

Sep.2008 - Dec.2011 R&D and Process chemist, Lab Leader, Exclusive Synthesis, Peptide and Oligonucleotides, Lonza AG, Visp, Switzerland

Activities: cGMP-API (CMO) projects (from grams to 100 kg) organization and management; Design and organisation of Research and Development; Training and supervising of technicians; Costing, Process Development and Optimization; Production Organization; Consulting organisation (Prof. F. Albericio); Transfer of technology between Lonza sites (Visp and Braine); Organisation of internal chemistry meeting; Literature Management; Innotech Management.

Expertise (Research) cGMP-oriented research and process development (synthetic route and process design); SPPS (Solid Phase Peptide Synthesis); HPPS (Homogeneous Phase Peptide Synthesis); Peptide Cyclization; Peptide Phosphorylation; Disulfide Bond Formation; Conjugation; Fluorescence Labeling; Diverse Peptide Modifications; DOE (Design of Experiments); QbD (Quality by Design) ect.

Expertise (Production) GMP Production Management; Mass Balance and Costing; SOP Drafting; Production Training; Risk Analysis; Coordination between Lab and Plant; Transfer of Technology; Project Management (from laboratory route selection to process development and GMP production; Coordination between the production unit and the pharmaceuticals)

Projects
(grams to 100 kg): - N-terminal of Statherin StN21 (Dental Peptide)
- Atrial Natriuretic factor (ANF32, Urodilatin)
- Vascoactive intestinal peptide (VIP)-Aviptadil
- Linaclotide
- [D-MeAla]3-[EtVal]4-Cyclosporin A
- Degarelix
- Goserelin
- Triptorelin
- Novexatin
- Activated Modified-nucleoside